1.
What is the best known mechanism of action for the drug
Lyrica (Pregabalin)?:
a. Impairs the arachidonic acid
pathway
b. Binds
directly to cholinergic receptors
c.
Modulate activity of A2D
calcium channels
d. Glutamate
receptor inhibition
2. Which of
the following is true regarding Zyvox (linezolid) ?:
a. First
commercially available member of the carbapenem class
b. Highly
effective against gram negative bacteria
c. Is only
available in IV form
d.
Acts by inhibiting
protein synthesis in bacteria
|
Answer
D. Zyvox (linezolid) is a
synthetic antibacterial agent of a new class of
antibiotics, the oxazolidinones. Its primary
spectrum of activity is in aerobic Gram positive
organisms. It is available in Oral and IV
formulations and works via inhibition of bacterial
protein synthesis. Click on this link for detailed
information:
http://zyvox.com/prescribingInfo.asp |
3. Lovenox (enoxaparin
sodium injection) should not be administered to patients with:
a.
Sensitivity to pork
b. Active
major bleeding
c.
Thrombocytopenia
d.
All of the above
4. When
treating a foot infection in a patient who is undergoing
dialysis, the correct dosing regimen for Zosyn (piperacillin/tazobactom)
is:
a. 3.375g
q24h
b. 4.5g q24h
c.
2.25g q12h
d. 3.375g
q12h
|
Answer C.
Patients who are renally
compromised should receive 2.25g q 12h per the
drug’s package insert. Zosyn is a broad spectrum
combination antibiotic that is often used for
empiric therapy. Click here for more information:
http://zosyn.com/dosing.asp |
5. Which of
the following can be added to lidocaine injection to yield a
better physiologic pH and less painful injection?:
a.
Sodium Bicarbonate
b.
Bupivacaine
c.
Methylparaben
d.
Ethyl alcohol
|
Answer A. The addition
of sodium bicarbonate can make for a more
comfortable injection and a more effective nerve
block due to the improvement of the pH pKa
relationship. See this PubMed article for some
interesting points:
CLICK for ARTICLE |
